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19 stories
Global Study of 6.1 Million People Finds Pain Rises Sharpest Before 55, Hits Lowest-HDI Nations Hardest
Harmonizing data from 6,125,459 people in 118 countries, McGill-led researchers built reference curves showing pain rises sharpest before a…
Urine RNA Test Detects 95% of Localized Bladder Cancers in 683-Sample Stanford Study
A Stanford Medicine study in Nature Medicine (October 2, 2026) found a urine RNA test detected 95% of localized bladder cancers and 90% of …
Single-Dose Topical Combination Clears Scabies in Pigs, Outlasting Ivermectin to Day 42
A QIMR Berghofer-led study in 32 pigs found a single topical dose of abametapir and flavesone cleared scabies mites and eggs through day 42…
REMODEL Trial: Semaglutide Misses Its Primary Kidney MRI Goals, but Biopsies Show a Fibrosis Signal
Nature Medicine published the REMODEL trial on October 1, 2026: semaglutide missed its coprimary MRI endpoints in 106 people with type 2 di…
Oncolytic Virus Added to Chemotherapy Shows a Survival Signal in Pancreatic Cancer, With Mixed Results on Significance
A phase 2b trial published in Nature Medicine on September 30, 2026 found VCN-01, an engineered oncolytic virus, added to chemotherapy leng…
Phase 3 Trial Finds Dual-Agonist Drug Survodutide Cuts Weight 13.1% in Adults With Type 2 Diabetes
A phase 3 trial published in NEJM on October 1, 2026 found that weekly survodutide, a dual glucagon/GLP-1 receptor agonist, produced up to …
Two Independent Trials Report Responses in KRAS G12D Cancers, but Nature Medicine Editorial Urges Caution
Two Nature Medicine trials of oral and intravenous KRAS G12D inhibitors report response rates of 41% and 63.3% in advanced solid tumors and…
Two Nature Medicine Trials of a Multi-Cancer Blood Test Reach Different Verdicts on the Same Day
Published the same day in Nature Medicine, PATHFINDER 2 and the NHS-Galleri trial reach different verdicts on GRAIL's Galleri blood test: s…
UK Biobank Study of 95,559 Wrist Trackers Links REM and Deep Sleep Stages to Risk of 83 Diseases
A PLOS Medicine phenome-wide study of 95,559 UK Biobank participants found that more REM and deep sleep, measured by wrist accelerometers, …
Reanalysis of Eight Mammography Trials Puts Breast Cancer Overdiagnosis Below 5%, Not 30-50%
A JNCI meta-analysis of eight randomized mammography trials, published 14 September 2026, finds overdiagnosis rates below 5% rather than th…
Danish Study of 2.1 Million Children Finds ADHD and Autism Diagnoses Increasingly Resemble the General Population
A JAMA Psychiatry study of 2.1 million Danish children finds that a decade of rising ADHD and autism diagnoses tracks a narrowing gap in bi…
Single-Infusion In Vivo CAR T-Cell Therapy Eases Four Neurologic Autoimmune Diseases in Small NEJM Trial
A 16-patient trial published in NEJM on September 3, 2026 tested a single-infusion lentiviral vector that generates CD19 CAR T cells inside…
First International Consensus Guideline for Personalized Phage Therapy Published in Nature Medicine
An international working group coordinated by Germany's DGI has published the first consensus guideline for personalized bacteriophage ther…
DRC's Bundibugyo Ebola Outbreak Passes 7,400 Cases and Is Now the Second Largest on Record
The Bundibugyo virus Ebola outbreak in the Democratic Republic of the Congo has passed 7,400 confirmed cases, WHO and ECDC data show, makin…
Gene Therapy Cuts Bleeding Episodes in Adolescents With Hemophilia B, Small Phase 1 Trial Finds
A phase 1 trial in Nature Medicine found that a single AAV gene therapy infusion cut bleeding episodes in 11 adolescents with hemophilia B,…
A Common Epilepsy Drug Is Linked to Longer Survival in an Almost Untreatable Childhood Brain Tumor
A retrospective Nature Medicine study (Sept. 17, 2026) led by Stanford Medicine finds children with diffuse midline glioma survived longer …
A Blood-Based Score Combining Ten microRNAs and CA19-9 Flags Early Pancreatic Cancer in a 1,785-Person Study
A prospective 1,785-person study published in Nature Medicine on September 16, 2026, found that PANXEON — a blood test combining ten microR…
Phase 1 Trial Finds a Cancer-Style T-Cell Engager Can Push Refractory Lupus Into Remission
A phase 1 trial of A-319, a CD3×CD19 bispecific antibody adapted from cancer therapy, pushed most of 12 treatment-resistant lupus patients …
Randomized Trial Finds Teclistamab Outperforms Standard Early Treatment in High-Risk Smoldering Myeloma
A phase 2 trial in Nature Medicine found that early teclistamab treatment produced deep, durable remissions in high-risk smoldering myeloma…