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Split cards contrast PATHFINDER 2's 60.3% positive predictive value against NHS-Galleri's missed primary endpoint, framed as "two trials, one blood test, different verdicts."

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Two Nature Medicine Trials of a Multi-Cancer Blood Test Reach Different Verdicts on the Same Day

Published the same day in Nature Medicine, PATHFINDER 2 and the NHS-Galleri trial reach different verdicts on GRAIL's Galleri blood test: strong predictive value in a single-arm US-Canada cohort, but a missed primary endpoint in a 142,250-person randomized UK trial.

EduFabTech · 1h ago · 5 min read