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3 item(s)

A single IV infusion generates CAR T cells inside the body that clear CD19-positive B cells, in a 16-patient trial spanning four autoimmune diseases with mostly mild side effects.
🩺 Health Study

Single-Infusion In Vivo CAR T-Cell Therapy Eases Four Neurologic Autoimmune Diseases in Small NEJM Trial

A 16-patient trial published in NEJM on September 3, 2026 tested a single-infusion lentiviral vector that generates CD19 CAR T cells inside…

EduFabTech · 2d ago · 4 min read
A single AAV gene-therapy infusion cut annualized bleeding from 13.9 to 0.5 episodes per year in 11 adolescents with hemophilia B, restoring liver production of factor IX.
🩺 Health Study

Gene Therapy Cuts Bleeding Episodes in Adolescents With Hemophilia B, Small Phase 1 Trial Finds

A phase 1 trial in Nature Medicine found that a single AAV gene therapy infusion cut bleeding episodes in 11 adolescents with hemophilia B,…

EduFabTech · 20 Sep 2026 · 4 min read
A CD3×CD19 bispecific antibody bridges a patient's T cell and a B cell, with key trial results — 12 patients, 80% reaching low disease activity, 60% meeting remission criteria.
🩺 Health Study

Phase 1 Trial Finds a Cancer-Style T-Cell Engager Can Push Refractory Lupus Into Remission

A phase 1 trial of A-319, a CD3×CD19 bispecific antibody adapted from cancer therapy, pushed most of 12 treatment-resistant lupus patients …

EduFabTech · 16 Sep 2026 · 4 min read