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Two experimental drugs, an oral pill and an IV nanoparticle, approach the smooth, pocket-less surface of the KRAS G12D protein, alongside the trials' headline response rates.
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Two Independent Trials Report Responses in KRAS G12D Cancers, but Nature Medicine Editorial Urges Caution

Two Nature Medicine trials of oral and intravenous KRAS G12D inhibitors report response rates of 41% and 63.3% in advanced solid tumors and pancreatic cancer, but an accompanying editorial calls the results a start, not a settled breakthrough.

EduFabTech · 41m ago · 5 min read