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Showing articles about nature medicine
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Global Study of 6.1 Million People Finds Pain Rises Sharpest Before 55, Hits Lowest-HDI Nations Hardest
Harmonizing data from 6,125,459 people in 118 countries, McGill-led researchers built reference curves showing pain rises sharpest before a…
REMODEL Trial: Semaglutide Misses Its Primary Kidney MRI Goals, but Biopsies Show a Fibrosis Signal
Nature Medicine published the REMODEL trial on October 1, 2026: semaglutide missed its coprimary MRI endpoints in 106 people with type 2 di…
Oncolytic Virus Added to Chemotherapy Shows a Survival Signal in Pancreatic Cancer, With Mixed Results on Significance
A phase 2b trial published in Nature Medicine on September 30, 2026 found VCN-01, an engineered oncolytic virus, added to chemotherapy leng…
Two Independent Trials Report Responses in KRAS G12D Cancers, but Nature Medicine Editorial Urges Caution
Two Nature Medicine trials of oral and intravenous KRAS G12D inhibitors report response rates of 41% and 63.3% in advanced solid tumors and…
Two Nature Medicine Trials of a Multi-Cancer Blood Test Reach Different Verdicts on the Same Day
Published the same day in Nature Medicine, PATHFINDER 2 and the NHS-Galleri trial reach different verdicts on GRAIL's Galleri blood test: s…
First International Consensus Guideline for Personalized Phage Therapy Published in Nature Medicine
An international working group coordinated by Germany's DGI has published the first consensus guideline for personalized bacteriophage ther…
Gene Therapy Cuts Bleeding Episodes in Adolescents With Hemophilia B, Small Phase 1 Trial Finds
A phase 1 trial in Nature Medicine found that a single AAV gene therapy infusion cut bleeding episodes in 11 adolescents with hemophilia B,…
A Common Epilepsy Drug Is Linked to Longer Survival in an Almost Untreatable Childhood Brain Tumor
A retrospective Nature Medicine study (Sept. 17, 2026) led by Stanford Medicine finds children with diffuse midline glioma survived longer …
A Blood-Based Score Combining Ten microRNAs and CA19-9 Flags Early Pancreatic Cancer in a 1,785-Person Study
A prospective 1,785-person study published in Nature Medicine on September 16, 2026, found that PANXEON — a blood test combining ten microR…
Phase 1 Trial Finds a Cancer-Style T-Cell Engager Can Push Refractory Lupus Into Remission
A phase 1 trial of A-319, a CD3×CD19 bispecific antibody adapted from cancer therapy, pushed most of 12 treatment-resistant lupus patients …
Randomized Trial Finds Teclistamab Outperforms Standard Early Treatment in High-Risk Smoldering Myeloma
A phase 2 trial in Nature Medicine found that early teclistamab treatment produced deep, durable remissions in high-risk smoldering myeloma…